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Medications

Targeting specific protein regions offers a new treatment approach in medulloblastoma

Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in Group 3 medulloblastoma ...

Surgery

Shoulder surgeons should rethink a common practice, new study suggests

A common practice of shoulder surgeons may be impairing the success of rotator cuff surgery, a new study from orthopedic scientists and biomedical engineers at Columbia University suggests. The work is published in the journal ...

Medical research news

Diseases, Conditions, Syndromes

Study confirms effectiveness of bivalent COVID-19 vaccine

A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to ...

Oncology & Cancer

Blocking gene may halt growth of breast cancer cells

Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical ...

Genetics

Using AI to improve diagnosis of rare genetic disorders

Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence. The ...